Organic Compounds
Tris(hydroxymethyl)aminomethane (33787)
meets analytical specification of Ph. Eur., assay (calc. to the dried substance) 99.0 - 100.5%
Overview
-aminomethane-analytical-77-86-1-1)
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An organic amine proton acceptor. It is used in the synthesis of surface-active agents and pharmaceuticals; as an emulsifying agent for cosmetic creams and lotions, mineral oil and paraffin wax emulsions, as a biological buffer, and used as an alkalizer. (From Merck, 11th ed; Martindale, The Extra Pharmacopoeia, 30th ed, p1424)
Specifications
General Information
- Synonyms
- 2-Amino-2-(hydroxymethyl)-1,3-propanediol, THAM, Tris base, Trometamol
- Linear Formula
- NH2C(CH2OH)3
- CAS Number
- 77-86-1
Physical Properties
- Physical Form
- Crystalline powder
- Odor
- Odorless
- pH
- 10.2 to 10.6 at 6 g/l (20 °C)
- Density
- 1.35 g/cm3 (23 °C)
- Vapor Pressure
- No data available hectopascal
- Solubility
- 26 g/l, Methanol (25 °C)
- Boiling Point/Range
- 288 °C (101 kPa)
- Melting Point/Range
- 170 °C
- Color
- Colorless
Safety Information
- Thermal Decomposition
- No decomposition if used as directed.
- Flammability
- Not auto-flammable
- Chemical Stability
- Stable under recommended storage conditions.
- Incompatible Materials
- Strong acids, Oxidizing agents, Nitrates
- Self Ignition
- The substance or mixture is not classified as pyrophoric.
International Transportation
- Harmonized System Code
- 29221900
General Information
- Synonyms
- 2-Amino-2-(hydroxymethyl)-1,3-propanediol, THAM, Tris base, Trometamol
- Linear Formula
- NH2C(CH2OH)3
- CAS Number
- 77-86-1
Physical Properties
- Physical Form
- Crystalline powder
- Odor
- Odorless
- pH
- 10.2 to 10.6 at 6 g/l (20 °C)
- Density
- 1.35 g/cm3 (23 °C)
- Vapor Pressure
- No data available hectopascal
- Solubility
- 26 g/l, Methanol (25 °C)
- Boiling Point/Range
- 288 °C (101 kPa)
- Melting Point/Range
- 170 °C
- Color
- Colorless
Safety Information
- Thermal Decomposition
- No decomposition if used as directed.
- Flammability
- Not auto-flammable
- Chemical Stability
- Stable under recommended storage conditions.
- Incompatible Materials
- Strong acids, Oxidizing agents, Nitrates
- Self Ignition
- The substance or mixture is not classified as pyrophoric.
International Transportation
- Harmonized System Code
- 29221900
- Synonyms : 2-Amino-2-(hydroxymethyl)-1,3-propanediol, THAM, Tris base, Trometamol
- Linear Formula : NH2C(CH2OH)3
- CAS Number : 77-86-1
- Physical Form : Crystalline powder
- Odor : Odorless
- pH : 10.2 to 10.6 at 6 g/l (20 °C)
- Density : 1.35 g/cm3 (23 °C)
- Vapor Pressure : No data available hectopascal
- Solubility : 26 g/l, Methanol (25 °C)
- Boiling Point/Range : 288 °C (101 kPa)
- Melting Point/Range : 170 °C
- Color : Colorless
- Thermal Decomposition : No decomposition if used as directed.
- Flammability : Not auto-flammable
- Chemical Stability : Stable under recommended storage conditions.
- Incompatible Materials : Strong acids, Oxidizing agents, Nitrates
- Self Ignition : The substance or mixture is not classified as pyrophoric.
- Harmonized System Code : 29221900
Property
Value
assay (calc. to the dried substance)
99.0 - 100.5 %
melting range
168 - 174 °C
loss on drying (105°C)
Max. 0.5 %
sulfated ash
Max. 0.1 %
pH (5 %, 20°C)
10 - 11.5
iron (Fe)
Max. 10 ppm
heavy metals (as Pb)
Max. 10 ppm
chloride (Cl)
Max. 100 ppm
related substances (TLC)
complying
IR spectrum
complying
appearance of the solution
complying