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Organic Compounds

Tris(hydroxymethyl)aminomethane (33742)

analytical reagent, buffer substance, assay min. 99.5%

An organic amine proton acceptor. It is used in the synthesis of surface-active agents and pharmaceuticals; as an emulsifying agent for cosmetic creams and lotions, mineral oil and paraffin wax emulsions, as a biological buffer, and used as an alkalizer. (From Merck, 11th ed; Martindale, The Extra Pharmacopoeia, 30th ed, p1424)

General Information

  • Synonyms
    • 2-Amino-2-(hydroxymethyl)-1,3-propanediol, THAM, Tris base, Trometamol
  • CAS Number
    • 77-86-1
  • Application
    • Industrial

Physical Properties

  • Melting Point/Range
    • 170 °C
  • Solubility in Water
    • 20 °C
  • Boiling Point/Range
    • 288 °C (101 kPa)
  • Color
    • Colorless
  • Solubility
    • 26 g/l, Methanol (25 °C)
  • Physical Form
    • Crystalline powder
  • Density
    • 1.35 g/cm3 (23 °C)
  • Vapor Pressure
    • No data available
  • pH
    • 10.2 to 10.6 at 6 g/l (20 °C)
  • Odor
    • Odorless

Safety Information

  • Thermal Decomposition
    • No decomposition if used as directed.
  • Self Ignition
    • The substance or mixture is not classified as pyrophoric.
  • Incompatible Materials
    • Strong acids, Oxidizing agents, Nitrates
  • Chemical Stability
    • Stable under recommended storage conditions.
  • Flammability
    • Not auto-flammable

International Transportation

  • Harmonized System Code
    • 29221900

General Information

  • Synonyms
    • 2-Amino-2-(hydroxymethyl)-1,3-propanediol, THAM, Tris base, Trometamol
  • CAS Number
    • 77-86-1
  • Application
    • Industrial

Physical Properties

  • Melting Point/Range
    • 170 °C
  • Solubility in Water
    • 20 °C
  • Boiling Point/Range
    • 288 °C (101 kPa)
  • Color
    • Colorless
  • Solubility
    • 26 g/l, Methanol (25 °C)
  • Physical Form
    • Crystalline powder
  • Density
    • 1.35 g/cm3 (23 °C)
  • Vapor Pressure
    • No data available
  • pH
    • 10.2 to 10.6 at 6 g/l (20 °C)
  • Odor
    • Odorless

Safety Information

  • Thermal Decomposition
    • No decomposition if used as directed.
  • Self Ignition
    • The substance or mixture is not classified as pyrophoric.
  • Incompatible Materials
    • Strong acids, Oxidizing agents, Nitrates
  • Chemical Stability
    • Stable under recommended storage conditions.
  • Flammability
    • Not auto-flammable

International Transportation

  • Harmonized System Code
    • 29221900
  • Synonyms : 2-Amino-2-(hydroxymethyl)-1,3-propanediol, THAM, Tris base, Trometamol
  • CAS Number : 77-86-1
  • Application : Industrial
  • Melting Point/Range : 170 °C
  • Solubility in Water : 20 °C
  • Boiling Point/Range : 288 °C (101 kPa)
  • Color : Colorless
  • Solubility : 26 g/l, Methanol (25 °C)
  • Physical Form : Crystalline powder
  • Density : 1.35 g/cm3 (23 °C)
  • Vapor Pressure : No data available
  • pH : 10.2 to 10.6 at 6 g/l (20 °C)
  • Odor : Odorless
  • Thermal Decomposition : No decomposition if used as directed.
  • Self Ignition : The substance or mixture is not classified as pyrophoric.
  • Incompatible Materials : Strong acids, Oxidizing agents, Nitrates
  • Chemical Stability : Stable under recommended storage conditions.
  • Flammability : Not auto-flammable
  • Harmonized System Code : 29221900